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SciB: Modalities Watch Blog

Welcome to Science for Bankers’ Modalities Watch Blog!

Science for Bankers is dedicated to all things therapeutics and modalities. Whether large molecules, small molecules, gene therapy, cell therapy, or RNA therapy. Subscribe and stay current on modalities.

Modalities Watch Blog Posts

Needle in vial

Tolerogenic vaccines for immune tolerance

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strand of RNA

Long non-coding RNAs have entered the chat

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RNA with protein

Could Circular ASOs become best-in-class?

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image of two proteins and a small molecule

The role of Cereblon in CELMoDs

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RNA with protein

New therapeutic modality: tiRNA

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The Emergence of Pro-bodies

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Molecular Glues, and now Molecular Gates

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cartoon of antibody binding to cell

pH Responsive Antibodies and Improved Targeting

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picture of antibodies

Sweeping antibodies (swAbs) – wash, rinse, repeat.

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Will LYTACs chase PROTACs into the clinic?

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Move over ADCs, here comes FDCs

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People with question marks above their heads

What is data exclusivity?

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Image of rubber stamp FDA approved and title Orange book and purple book

The Orange Book and Purple Book

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Therapeutics at the FDA: paths to approval

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BLA text with checkmark

2023 Year in Review:  approved BLAs

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image with check mark and the text NDA

2023 Year in Review:  approved NDAs

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Image with three icons showing a person running with an arrow trending up

Biosimilar Therapeutics: generics of biologic drugs

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Letters ANDA beside a mountain

Therapeutic FDA approvals: the rise of the ANDA

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image of FDA building

Therapeutics in the U.S.: why are there NDAs and BLAs? 

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Image with icons of needle, syringe, pill bottle, and building with CDER, CBER and FDA text

Approval and Regulation of Therapeutics and Modalities at the FDA

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Therapeutics and Modalities: at the intersection of science and investing

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A circle divided into the five therapeutic classes of small molecules, large molecules, gene therapy, cell therapy, and RNA therapy

Therapeutics and Modalities 101

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